What is the adult dose of adrenaline injection 1mg/ml and its common use?

• A. 0.5 mg
• B. 1.0 mg
• C. 0.3 mg
• D. 0.15 mg

Answer: (A)

Adrenaline at a concentration of 1 mg/mL is used intramuscularly in adults for acute anaphylaxis. The standard dose is 0.5 mg given into the muscle, which delivers a rapid effect. This amount works quickly because adrenaline acts on both alpha and beta receptors: the alpha-adrenergic action constricts dilated blood vessels, raising blood pressure and reducing swelling around the airway, while the beta-adrenergic action bronchodilates to improve breathing. The intramuscular route provides fast absorption with a safer profile in emergency settings outside hospital. The common use of this dose is to treat life-threatening allergic reactions, where rapid reversal of airway compromise and hypotension is essential. If symptoms persist, a second 0.5 mg dose can be given after several minutes while additional medical care is arranged.